HEALTH RELATED QUALITY OF LIFE IN PATIENTS WITH END STAGE RENAL DISEASE UNDERGOING MAINTENANCE HAEMODIALYSIS

Abstract

Introduction: Assessment of Health-related quality of life (HRQOL) is an acceptable modality to determine the physical, social and emotional wellbeing of patients with Chronic Kidney Disease Objective: The study was designed to assess the Quality of life of patients on Maintenance Haemodialysis and also identify characteristics that may be associated with their worsening quality of life. Methods: An observational cross-sectional study involving Adult ESRD Patients on Maintenance HD at four different units in South Western part of Nigeria. Results: The SF-36 scores for the 8 domains were Physical functioning - 50.0± 27.9, Role functioning – physical - 36.6 ± 40.4, Bodily pain - 60.3 ± 26.9, General Health - 47.4 ± 22.8, Vitality - 51.1± 19.7, Social functioning - 39.0± 30.6, Role functioning – Emotional - 52.9 ± 42.8, Mental Health - 70.3 ± 18.2. The frequency of HD per week was significantly correlated with Physical functioning (r = 0.436;p=0.004), Role – physical (r= 0.435;p=0.004), Bodily Pain (r=0.358;p=0.022),General Health (r=0.361;p=0.021), Social Functioning (r=0.576;p<0.001), Role – Emotional (r=0.518;p<0.001) and Mental Health (r=0.313;p=0.046). The total serum protein, serum albumin levels and packed cell volume correlated with more than one SF-36 quality of life domains. Conclusion: HRQOL is suboptimal in our end stage renal disease (ESRD) patient population. The packed cell volume and serum albumin levels were significantly correlated with the HRQOL.